Hillary, and C Rice were speakers at a dinner of the Global Business Coalition on HIV-AIDS, helping raise $1.3 million.
Clinton drew loud applause when she called on the Bush administration and Congress to recognize the importance of condoms in the fight against AIDS.
"There is a great deal of political pressure to only talk about abstinence, and to deny support for condoms and education on using them," Clinton said. "This policy will lead to the unnecessary deaths of many people."
She said girls and women were increasingly at risk, especially in the countries most affected.